Archive for the ‘MOD’ Category

Celebrating Jonas Salk, MD

Monday, October 27th, 2014

Jonas SalkTomorrow is Jonas Salk’s 100th birthday. Salk’s eldest son Peter Salk, MD, recently came to the March of Dimes National Office to speak about his father and The Jonas Salk Legacy Foundation. It was touching to hear the history and personal stories about Salk.

Peter recounted how his father had initially thought he would become a lawyer or congressman. But college chemistry set him in a new direction. While attending NYU Medical School, a microbiology class inspired him to begin his quest in vaccine research. Before long, he became one of the most famous researchers of the 20th century.

Jonas Salk, MD. was intrigued by the idea of creating a vaccine from inactivated versions of a virus. He first worked on an inactivated flu vaccine but he is most remembered for his pioneering work in creating a polio vaccine in the midst of the polio epidemic.

Basil O’Connor, President of the National Foundation for Infantile Paralysis (now known as the March of Dimes) was intrigued by Salk’s research and decided to fund Salk’s efforts to develop the vaccine against infantile paralysis, also known as polio. In 1955, it was announced that the Salk vaccine was safe and effective against this disabling, sometimes fatal infection. Salk’s vaccine rapidly reduced polio infections by 97%. With the help of the Salk vaccine and later the Sabin oral vaccine, both developed with March of Dimes funding, polio infections have been eliminated from the United States for nearly 3 decades. Polio still occurs, however, in some developing countries.

Salk vaccineIn addition to being a preeminent physician and researcher, Salk had a philosophical side. One question Salk would ask is “Are we being good ancestors?”  It was the foundation on which he based his life, and his unending quest to help improve mankind. Peter ended the presentation with one of Jonas’ quotes: “Hope lies in dreams, in imagination and in the courage of those who dare to make dreams into reality.” Jonas believed each person was responsible for making a difference in the world. By eradicating polio in the United States, Jonas Salk fulfilled his own dream.

You can learn more about Jonas Salk’s life and contributions by watching this historical footage reel.

The March of Dimes remembers, honors and celebrates Jonas Salk’s accomplishments as we continue our mission to improve the health of babies.

March of Dimes’ researchers hard at work

Friday, October 3rd, 2014

research_birthdefectsresearch_rdax_50Did you know that in 2014, the March of Dimes invested about $25 million in research to defeat premature birth and other health problems? Scientific research has been a main focus of the March of Dimes since it was founded 75 years ago. March of Dimes-funded researchers created the first safe and effective vaccines for epidemic polio, and we haven’t stopped trying to improve the health of all babies since then.

The March of Dimes has pioneered genetic research, promoted the B vitamin folic acid to prevent birth defects, fought for lifesaving newborn screening tests– and so much more. Here are some recent examples of our work:

  • Cytomegalovirus (CMV) causes birth defects in 8,000 babies each year. Pregnant women can pass the virus on to their baby before or during birth. The March of Dimes is funding research on protecting against CMV in women of childbearing age, thereby protecting babies.
  • Novel gene therapy: Scientists have long been seeking to develop gene therapy. However, they have run into a number of obstacles. A recent March of Dimes grantee is attempting to find a new way around these obstacles. He is using a novel form of gene therapy called “gene editing.” Instead of replacing the faulty gene, this new technology attempts to find and fix the mutation (change) in the gene.

In 2003, the March of Dimes launched the Prematurity Campaign to help families have full-term, healthy babies. We now have two Prematurity Research Centers –Stanford University and the Ohio Collaborative. These transdicsiplinary centers recognize that preterm birth is a complex disorder with many contributing factors. At both centers, scientists are coming together to examine the problem of preterm birth from many angles. Some highlights of ongoing research include:

  • Progesterone signaling in pregnancy maintenance and preterm birth: Progesterone is a key pregnancy hormone. It is thought to play a role in preventing contractions until term, but we don’t know how it does this. Progesterone treatment is one of the few available treatments to help prevent repeat singleton preterm delivery in women who have already had a premature birth. However, we do not know why progesterone treatment works in some women but not others. A better understanding of the exact role progesterone plays in maintaining pregnancy may lead to new ways to prevent or treat preterm labor.
  • Microbiome and preterm birth: The microbiome refers to the bacteria and other microbes that live inside our bodies. Recent genetic technologies (DNA sequencing) have identified many new organisms, most of which don’t harm our health. Scientists are analyzing changes in the microbiome in samples from term and preterm pregnancies. The goal is to find out if specific microbes or changes in the microbiome may contribute to premature birth. This information could lead to better ways to predict and prevent premature birth.

The March of Dimes expects to open two additional Prematurity Research Centers in the near future.  You can read more about our infant health, birth defects, and prematurity research on our website.  The March of Dimes continues to do all it can to give every baby a healthy start in life.

 

Thanks for your support!

Monday, April 28th, 2014

marching feetHundreds of thousands of you joined us this weekend for March for Babies! We had great success, lots of fun, met new people and old friends. To all of you who participated, in person or through a donation, we sincerely thank you for your support.

Nacersano.org, our Spanish-language site

Monday, March 31st, 2014

nacersano homepage

Hispanic women have babies at a greater rate each year than any other racial or ethnic group in the United States, making this population the fastest growing group. And now, Spanish-speaking women and families can easily find much-needed information on how to have a healthy pregnancy and a healthy baby online at nacersano.org.

Nacersano.org, the March of Dimes Spanish-language site, offers valuable information on the specific health needs of the Hispanic community, including on the importance of folic acid, a B vitamin that helps prevent serious birth defects of the brain and spine known as neural tube defects (NTDs).

Babies born to Hispanic women are about 20 percent more likely to have a neural tube defect than non-Hispanic white women. While this disparity is not well understood, one reason may be that Hispanic women have a lower intake of folic acid. In the United States, wheat flour is fortified with folic acid, but corn masa flour is not.

The March of Dimes, through its educational print and online initiatives, is working to raise awareness about the need for folic acid among Hispanic women. All women of childbearing age, whether or not they’re planning to get pregnant, should take a multivitamin with 400 micrograms of folic acid every day, beginning before pregnancy and continuing into the early months of pregnancy. This is the best way to get the recommended amount of folic acid to prevent NTDs. Eating foods rich in folate (the natural form of folic acid) or fortified with folic acid is another way to consume this essential vitamin.

Visitors to nacersano.org can find dozens of recipes from various Latin America cultures that provide at least 10 percent of the recommended daily amount of folic acid. Users can also submit their own folic acid rich recipes to the site.

“It’s such an easy thing to make folic acid a part of your daily routine, and it can provide a major benefit to your future family,” says José F. Cordero, MD, MPH, dean of the School of Public Health University of Puerto Rico and a member of the March of Dimes national Board of Trustees. “About half of pregnancies are unplanned, so women should take folic acid daily to give your babies the healthiest start in life.”

Nacersano.org also features hundreds of health articles, ovulation and due date calculators, and educational videos to help Hispanic women and families be healthy before, during and after pregnancy.

Visitors can also ask questions about folic acid and nutrition, preconception, pregnancy and baby health. March of Dimes health experts provide personalized answers by email within 48 hours in Spanish and English. Visitors can also sign up to receive monthly free newsletters on preconception and pregnancy health, read and comment on the blog, and stay connected through various social media channels.

So, if you’re more comfortable with the Spanish language, “like” us on Facebook.com/nacersano and follow us on @nacersano and @nacersanobaby on Twitter.

Anne Geddes supports March of Dimes

Monday, March 24th, 2014

Jack Holding Maneesha

World-renowned photographer Anne Geddes is lending her talent to support the March of Dimes Prematurity Campaign and World Prematurity Day 2014. She will be taking an exclusive image this week that will be released specifically for the campaign in November. We couldn’t be more thrilled!

Ms. Geddes is a longtime advocate for children and babies, and says the issue of preterm birth is close to her heart. One of her earliest and most iconic images is this one called “Jack Holding Maneesha,” a photograph of a baby born prematurely at 28 weeks. This year, Maneesha celebrates her 21st birthday.

If you want to know more about this exciting collaboration, read our news release.

Watchdog group honors March of Dimes

Friday, February 28th, 2014

We are thrilled to announce that the March of Dimes is being honored as a top charity by Philanthropedia, a division of GuideStar. Philanthropedia is a web-based nonprofit group that rates charities according to their financial responsibility and outstanding work, helping donors to give wisely. Philanthropedia’s panel of 74 experts identified the March of Dimes as 1 of 16 high-impact nonprofits working in the field of people with disabilities, and named it second in that category.

“We are pleased and humbled to be cited by Philanthropedia experts as a top nonprofit in our field,” says Dr. Jennifer L. Howse, president of the March of Dimes.

Starting in 1955 with a signature victory to eliminate polio in the United States, the March of Dimes has led many successful public health campaigns that improved infant health, including:

• Reducing serious birth defects of the brain and spine by 26 percent through folic acid fortification of the nation’s grain foods in the late 1990s;

• Bringing mandatory newborn screening programs to every state to ensure that each baby is tested for more than 30 conditions that, if undetected and untreated, can lead to serious disability or death;

• Launching a nationwide prematurity prevention campaign. The March of Dimes recently announced that the U.S. preterm birth rate dropped for the sixth consecutive year in 2012 to 11.5 percent, a 15-year low.

In addition to this new honor, the March of Dimes is a Better Business Bureau Accredited Charity and meets all 20 standards listed on the BBB Wise Giving Alliance Web site Give.org.

“We are very proud of our fiscal stewardship,” added Dr. Howse. “We receive financial support from more than 3 million volunteers, thousands of corporate sponsors, and state and federal agencies. With this support, we fund the innovative research, education, and community programs that are designed to deliver results and bring us closer to that day when every baby in every community is born healthy.”

Prematurity Research Initiative

Friday, January 31st, 2014

In 2005, the March of Dimes began the Prematurity Research Initiative (PRI), which funds research into the causes of prematurity. More than $15 million has been awarded to 43 grantees over the past 6 years. Some PRI grantees are exploring how genetics or a combination of genetic and environmental factors may influence a woman’s chances of going into labor prematurely. Others are examining how infections may trigger early labor. One of every three premature births can be attributed an infection in a woman’s uterus, which may have presented with no symptoms.

Treating preterm labor –
PRI grantees also are exploring new ways to treat preterm labor. Some are studying how the body normally suppresses uterine contractions until a baby reaches full term, so that new drugs can be developed to prevent or stop preterm labor.

Saving preemies’ lives –
In addition to PRI support, the March of Dimes funds prematurity research through its national research program. Grantees are improving the care of premature babies by developing new ways to help prevent or treat common complications of prematurity. For example, researchers helped develop surfactant treatment, which has saved tens of thousands of premature babies with breathing problems.

Transdisciplinary research centers –
A novel approach to address the complex problem of preterm birth and the resulting prematurity is a transdisciplinary effort within which many diverse disciplines work together by integrating research. By working together, they can examine this problem from new perspectives in ways that individual studies do not allow. The March of Dimes has established the first transdisciplinary research center and plans to promote the establishment of several more.

Our new national ambassador

Monday, January 27th, 2014

2014-ambassador-aidan

The March of Dimes is excited to introduce our 2014 National Ambassador, six year old Aidan Lamothe. Born 12 weeks early, Aidan weighed just 3 lbs and spent 7 weeks in a NICU receiving treatments for breathing problems, his low birthweight, and other prematurity related issues.

Each year on his birthday, Aidan visits the NICU and says “thank you” to the doctors and nurses. Even as a young child, he understood how serious it is to be born prematurely and decided he wanted to volunteer to tell his story to help others. As our National Ambassador, he will travel with his parents to help raise funds and awareness for premature birth.

Welcome Aidan!

You don’t know what you don’t know

Tuesday, January 7th, 2014

woman-on-laptopYes. That makes sense. No, I’m not being funny. You don’t know what you don’t know.

This is why we have updated our website to include article libraries for each subject category or topic. We have hundreds of articles on our website, on topics such as pre-pregnancy, pregnancy, birth and after birth, health problems, caring for your baby, your baby’s health, complications, loss and grief, research, advocacy, and much more.

When you search our website and read an article, a box appears to the right of the text titled “In this topic” where you will find other articles related to your topic. At the bottom of the box you can click on “See all in library” where you will then see additional articles, common questions and special features, on your topic.

Once you see all of the titles in the library, you may realize that you need to know more about a topic. Simply click on it to read all about it. For example, here is our article library for Getting ready for pregnancy. Until you see all of the other topics in the article library, you may not know what you don’t know!

We hope this info helps you in your knowledge search and that you find it easy to navigate. We’d love to hear your comments!

Happy reading.

PREEMIE Act signed into law

Tuesday, December 3rd, 2013

On Nov. 27th, President Barack Obama signed into law S. 252, the PREEMIE Reauthorization Act, a bill to reauthorize federal research, education and intervention activities related to preterm birth and infant mortality.

“The PREEMIE Act represents the federal government’s commitment to reducing the devastating toll of preterm birth,” stated Dr. Jennifer L. Howse, President of the March of Dimes.  “By signing this bill into law, President Obama has enabled vital research and education on the prevention of prematurity to continue.  The March of Dimes is deeply grateful to him, as well as the authors of the PREEMIE Act – Senators Lamar Alexander (R-TN) and Michael Bennet (D-CO) and Representatives Anna Eshoo (D-CA) and Leonard Lance (R-NJ) – for their tireless efforts to ensure that no baby is born too soon.

“Today, one in every nine U.S. infants is born preterm.  Due to concerted efforts by the March of Dimes and our partners, this number has gone down for the past six consecutive years, but it is still too high.  Prematurity can lead to a host of adverse health consequences for these babies and place a terrible strain on their families.  In addition, preterm birth carries a significant cost to businesses and our economy.  The average premature birth costs 12 times as much as a healthy birth.  The PREEMIE Reauthorization Act will sustain the vital federal investment in promoting healthy pregnancies, healthy infants, and healthy families.”

Preterm delivery can happen to any pregnant woman; in many cases, the cause of preterm birth is unknown. Preterm birth is the leading cause of neonatal death, and those babies who survive are more likely to suffer from intellectual and physical disabilities. In addition to its human, emotional, and financial impact on families, preterm birth places a tremendous economic burden on the nation.  A 2006 report by the Institute of Medicine found the cost associated with preterm birth in the United States was $26.2 billion annually, or $51,600 per infant born preterm. Employers, private insurers and individuals bear approximately half of the costs of health care for these infants, and another 40 percent is paid by Medicaid.

S. 252 was endorsed and strongly supported by a wide range of organizations, including the American Academy of Pediatrics, the American Congress of Obstetricians and Gynecologists, the Association of Women’s Health, Obstetric and Neonatal Nurses, the Association of Maternal and Child Health Programs, the Association of State and Territorial Health Officials, and the National Association of City and County Health Officers, and more.

The original PREEMIE Act (P.L. 109-450) brought the first-ever national focus to prematurity prevention.  The Surgeon General’s Conference on the Prevention of Preterm Birth required by the Act generated a public-private agenda to spur innovative research at the National Institutes of Health (NIH) and Centers for Disease Control and Prevention (CDC) and support evidence-based interventions to prevent preterm birth. The PREEMIE Reauthorization Act reauthorizes critical federal research, education and intervention activities related to preterm birth and infant mortality.