Posts Tagged ‘skull’

Valproate sodium and related products linked to birth defects

Thursday, December 3rd, 2009

Today the U.S. Food and Drug Administration issued a statement about the increased risk of birth defects when a fetus is exposed to valproate sodium and related products (valproic acid and divalproex sodium).

The birth defects are neural tube defects, craniofacial defects, and cardiovascular problems. A neural tube defect is a defect of the brain and spinal cord. A craniofacial defect affects the face and the skull.

Valproate sodium and its related products may be used to treat migraine headaches, certain seizures and other conditions. If a woman is taking any of these products, she should talk to her health care provider, preferably before she gets pregnant. The risk of birth defects is especially high during the first trimester.