Posts Tagged ‘surfactant’

What are antenatal corticosteroids?

Friday, February 9th, 2018

Preterm labor is labor that happens too early, before 37 weeks of pregnancy. If you have preterm labor, your health care provider may recommend antenatal corticosteroids to help speed up your baby’s lung development and reduce the chances of some complications.

How do antenatal corticosteroids work?

There are two types of corticosteroids that may be used if you’re in preterm labor, betamethasone and dexamethasone. Both of these steroids help your baby’s lungs produce surfactant. Surfactant is a protein that helps keep the small air sacs in the lungs from collapsing. When a baby is born full-term, her lungs produce surfactant naturally. But babies born premature do not produce enough surfactant, and that means the air sacs in the lungs do not expand the way they should. This results in premature babies having breathing difficulties.

When should you get antenatal corticosteroids?

The American College of Obstetrics and Gynecology (ACOG) recommends a single course of corticosteroids for pregnant women who are at-risk of premature birth within the next 7 days. This includes women whose membranes have ruptured and women pregnant with twins or other multiples. If you’re pregnant and at-risk for giving birth early, talk to your health care provider and discuss the best treatment options for your specific situation.

Are antenatal corticosteroids effective?

If you’re in preterm labor and you receive antenatal corticosteroids, your baby’s chances of having certain health problems after birth are reduced, including:

  • Respiratory Distress syndrome (RDS). This is a breathing problem most common in babies born before 34 weeks of pregnancy. Babies with RDS don’t have enough surfactant and it results in breathing problems.
  • Intraventricular hemorrhage (IVH). This is bleeding in the brain. It usually happens near the ventricles in the center of the brain. A ventricles is a space in the brain that’s filled with fluid.
  • Necrotizing enterocoloitis (NEC). This is a problem with a baby’s intestines. It can cause feeding problems, a swollen belly and diarrhea. It sometimes happens 2 to 3 weeks after a premature birth.

Are there side effects?

Possible side effects of medicines like betamethasone and dexamethasone for mom may include fluid build-up in the body and increased blood pressure. There are no side effects for your baby.

If you’re at risk of giving birth early, talk to your provider about antenatal corticosteroids and how they may be able to help your baby. You can learn more about other treatments for preterm labor on our website. And all pregnant women should learn the signs and symptoms of preterm labor. If you have even one sign or symptom, call your health care provider. If you’re having preterm labor, getting help quickly is the best thing to do.

What is a respiratory therapist?

Monday, October 30th, 2017

If your baby is in the NICU, you know that there are a lot of people caring for her and helping her to get stronger each day. One of those NICU team members may be a respiratory therapist. A respiratory therapist (or RT) cares for babies with breathing problems.

When your baby first arrives in the NICU, a respiratory therapist evaluates her breathing. The RT looks to see if your baby is breathing too fast, if the breaths are shallow, or if she’s struggling to breathe. Then, together with the rest of the NICU team, the RT develops a treatment plan to help care for your baby.

Here are some common conditions that a respiratory therapist may see in the NICU:

Breathing problems: Premature babies often have breathing problems because their lungs are not fully developed. Full-term babies also can develop breathing problems due to complications of labor and delivery, birth defects and infections.

Apnea: Premature babies sometimes do not breathe regularly. A baby may take a long breath, then a short one, then pause for 5 to 10 seconds before starting to breathe normally. This is called periodic breathing. Apnea is when a baby stops breathing for more than 15 seconds. Apnea may be accompanied by a slow heart rate called bradycardia. Babies in the NICU are constantly monitored for apnea and bradycardia (often called “A’s and B’s”).

Respiratory distress syndrome (RDS): Babies born before 34 weeks of pregnancy often develop RDS. Babies with RDS do not have enough surfactant, which keeps the small air sacs in the lungs from collapsing.

Pneumonia: This lung infection is common in premature and other sick newborns. A baby’s doctors may suspect pneumonia if the baby has difficulty breathing, if her rate of breathing changes, or if the baby has an increased number of apnea episodes.

Many babies who need treatment for breathing problems benefit from respiratory therapy. In fact, neonatal respiratory therapy has become its own medical sub-specialty. A neonatal-pediatric RT is trained to use complex medical equipment to care for the smallest babies with mild to severe breathing challenges. They visit their patients daily or as often as needed and are an important part of your baby’s NICU team.

Have questions? Text or email AskUs@marchofdimes.org.

Three quarters of a century young (yes – we’re 79 years old!)

Monday, December 19th, 2016

fdr-warm-springs-kidsIt’s that time of year, when magazines are full of stories and photos of the year in review, and people look back to take stock of their accomplishments. This post is taking it a step further…here is a celebration of our past 79 years!

Why the dimes? (we get this question a lot)

The March of Dimes was started in 1938 when Franklin Roosevelt’s personal struggle with polio led him to create the National Foundation for Infantile Paralysis. It was a time when polio was on the rise nationwide. The name for the fundraiser “March of Dimes” was coined by comedian and radio personality Eddie Cantor as a pun on a popular movie newsreel of the era, The March of Time. Cantor asked his radio audience to send dimes to the White House to help polio patients and support research. After billions of dimes were received, the organization became known as the March of Dimes. The end result of this effort was the development of the polio vaccines, which have almost completely rid the world of this disabling disease.

check in boxIt is very unusual for a nonprofit organization to fulfill its mission as completely as that of the March of Dimes. So, when the March of Dimes checked off the box on the successful development of the Salk and Sabin polio vaccines, we turned our focus to that of preventing birth defects and infant mortality. With thousands of birth defects on record, we’ve had our hands full.

Our work after polio

The March of Dimes has funded research looking for the underlying genetic causes of birth defects to help us better understand what can go wrong and hopefully how to prevent them. We’ve funded research into the development of surfactant therapy to treat breathing problems in premature infants, which has saved thousands of lives since 1990. We’ve successfully championed and promoted newborn screening so that more infants with devastating conditions are identified and treated in a timely manner; and we led the campaign to add folic acid to grain foods in the United States, thereby reducing serious birth defects of the brain and spine by 27%.

We began educating the public on how to have a healthy pregnancy by producing a robust website of articles, print materials, this blog, and using social media to help women understand what they can do to have a full-term, healthy baby. We began answering individual health questions from the public in 1996 and still continue to answer thousands of questions every year.

But we didn’t stop there.

Our work with babies, birth defects and infant mortality provided a natural transition into fighting premature birth, the number 1 cause of deathPassing the time while your baby is in the NICU among babies in the U.S. Nearly 1 in 10 babies is born prematurely. Despite the advances in neonatal medicine, many babies still die, and the ones who survive often face a lifetime of disability – from mild to severe. In short, it is simply something that we knew we needed to fight.

So, in 2003 we launched our Prematurity Campaign. And in 2011, we launched the first of five prematurity research centers, each one staffed by the best and brightest scientists, and each one focused on a different aspect of prematurity. The best part of this 5-pronged approach is that the researchers all talk to one another and collaborate, encouraging synergy. Our goal is to be as successful with ending prematurity as we were with eliminating polio.

We also continued in the quest to allow folic acid to be added to corn masa flour in the U.S., and…drum roll please…we were successful this year! This is very important for the Hispanic community as corn masa flour is a staple for many Hispanic families. Fortifying corn masa flour products such as tortilla chips, tacos, and tamales, with folic acid will help prevent more devastating neural tube birth defects like Spina Bifida.

Wait…there’s more…

In the meantime, another related mission has surfaced – stopping the Zika virus. The devastating effects that Zika can have on a developing baby are well documented (microcephaly, congenital Zika syndrome, and developmental delays).

The March of Dimes led a coalition of almost 100 organizations to educate Congress about the dangers of Zika and was successful in the passage of federal funding to combat the virus. We continue to raise awareness with our #ZAPzika campaign to let women know how to protect themselves. By working with the CDC, we‘re educating the public about this virus so that pregnant women can protect themselves and their babies from Zika.

Yes. We’ve been very busy. The past 78 years have gone by quite fast.

Is there anything else in our future? Glad you asked!

A new March of Dimes President.

With the start of 2017, we will be under the leadership of President, Stacey D. Stewart, MBA, a woman of experience, intelligence, creativity and integrity. We’re so excited to welcome her.

The mission of the March of Dimes is to improve the health of babies by preventing birth defects, premature birth and infant mortality.

We are confident that under the leadership of Ms. Stewart, we will once again check off the box on a mission accomplished.