Posts Tagged ‘valproate sodium’

Valproate for migraines is unsafe during pregnancy

Tuesday, May 7th, 2013

 

The U.S. Food and Drug Administration (FDA) is warning women and their health providers that Valproate products, a group of medicines normally used to treat seizures, is unsafe for pregnant women to use to treat migraines. A recent study found that the products may harm brain development in babies, leading to lower IQs than healthy babies later in life. FDA also says women who aren’t pregnant and are using Valproate products should use birth control.

Valproate products are usually used to treat epilepsy, a brain disorder that causes you to have frequent seizures, and bipolar disorder, a serious mental illness that leads to unusual mood changes. FDA says that Valproate products may still be used to treat epilepsy and bipolar disorder in pregnancy, but only if no other treatment is suitable.

If you’re pregnant or thinking about getting pregnant, talk to your health provider about any medicines you take. Some medicines you take can hurt your baby. Once you’re provider knows what medicines you take, she can tell you which ones are safe and which ones you need to stop taking.

Learn more about the FDA announcement on Valproate.

 

Valproate sodium and related products linked to birth defects

Thursday, December 3rd, 2009

Today the U.S. Food and Drug Administration issued a statement about the increased risk of birth defects when a fetus is exposed to valproate sodium and related products (valproic acid and divalproex sodium).

The birth defects are neural tube defects, craniofacial defects, and cardiovascular problems. A neural tube defect is a defect of the brain and spinal cord. A craniofacial defect affects the face and the skull.

Valproate sodium and its related products may be used to treat migraine headaches, certain seizures and other conditions. If a woman is taking any of these products, she should talk to her health care provider, preferably before she gets pregnant. The risk of birth defects is especially high during the first trimester.